NTD's in the News this week (31 March thru 6 April 2013)

23000 dengue cases recorded in 3 months

Sun.Star - ‎Apr 5, 2013‎

THE Department of Health (DOH) has recorded over 23,000 cases of dengue in the country in the first three months of the year.

NIAID grants $2.2 mn fund to VaxInnate for developing dengue vaccine

pharmabiz.com - ‎6 hours ago‎

The grant provides funding of $2.2 million over a period of three years to develop a recombinant tetravalent dengue vaccine using VaxInnate's proprietary technology.

Dengue fever is back in Madurai

The Hindu - ‎5 hours ago‎

The dengue threat is back as health officials have admitted fever outbreak in several villages in Madurai district. As it happened last year, it is the Melur block that is kept under scanner as a large number of fever cases are being reported from ...

Dengue cases rising

Solomon Star - ‎Apr 4, 2013‎

“We have more than four hundred dengue fever confirmed cases already reported and another thousand plus suspected cases,” World Health Organization's (WHO) Health Promotion and Communications Officer, Saula Volavola said.

Meeting on anti-dengue campaign

Pakistan Observer- ‎15 hours ago‎

Administrator Saira Umar briefed Special Secretary Local Government regarding working of different departments regarding anti dengue campaign in Data Ganj Baksh Town Lahore. She told that teams are visiting Graveyards, Junkyards, Pounds and ...

Guinea worm disease on the way out

ABC Online - ‎Apr 3, 2013‎

Guinea worm disease on the way out. The Guinea worm's days of using the human body as an incubator for its one-metre uterus are numbered.

Gene mutation linked to leprosy in Indians

The Hindu - Apr 3, 2013

In a new finding, a mutation in TAP1 gene has been associated with susceptibility to leprosy in Indians. TAP1 gene is one of the several genes that regulate the immune response and its variations were earlier implicated in tuberculosis and auto-immune ...

Rising dengue cases prompt Kidapawan City fumigation drives

Philippine Star - ‎Apr 2, 2013‎

COTABATO CITY, Philippines - Health workers started on Tuesday massive fumigation operations in several villages in Kidapawan City following a rise in cases of dengue fever in recent weeks. The first area the city health office fumigated with anti ...

'Old tyre shops at Nishtar town must be taken to task'

PakistanToday.com.pk - ‎18 hours ago‎

Punjab Excise and Taxation Department Secretary Capt (r) Zahid Saeed, while presiding over Dengue Control Committee Nishter Town, directed the Nishter Town Administration to take action against owners of old tyre shops who were not following the ...

NRHM takes steps to check dengue menace

Times of India - ‎Apr 3, 2013‎

"As dengue-causing mosquitoes breed in stagnant water, we are spraying larvicide in the drains. About 100 spraying machines and 108 people have been engaged for this purpose.

Dengue Fever No Longer Just A Visitor To Florida Keys

NPR (blog) - ‎Mar 13, 2013‎

Thanks to efforts from Key West health officials to combat mosquitoes, dengue transmission in the area has slowed dramatically, says the CDC's Jorge Munoz-Jordan, who led the study.

Sethi for joint efforts to eliminate dengue

The News International - ‎Apr 1, 2013‎

He said that a vigorous public awareness drive should also be initiated regarding the importance of sanitation and preventive measures against dengue. He directed that all departments concerned should take effective measures in a well-coordinated ...

Ignoring dengue guidelines: FIRs against 27 tyre shops, scrap yards and ...

The Express Tribune - ‎Apr 2, 2013‎

In the last month, the Environment Protection Department (EPD) issued notices to 1,119 and lodged FIRs against 27 tyre shops and warehouses, scrap yards and construction sites for not following dengue-prevention guidelines. A total of 4,951 places were ...

VaxInnate Wins $2.2M NIAID Grant for Dengue Vaccine

Genetic Engineering News - ‎Apr 4, 2013‎

The grant will fund development of a recombinant tetravalent dengue vaccine using VaxInnate's technology, which involves genetically fusing vaccine antigens to the bacterial protein flagellin, with the goal of dramatically improving the potency ...

Cotabato records 156% rise in Dengue cases - DOH

Manila Bulletin

 - ‎Apr 4, 2013‎

DENGUE FUMIGATION (April 4, 2013) - The local health office in Zamboanga City has started their dengue fumigation activities and have targeted suspected areas where mosquitoes with the deadly disease are hiding and hatching their eggs.

Rain disrupts surveillance system,anti-dengue fever activities

The News International - ‎Apr 3, 2013‎

The district allied departments have done nothing significant so far to eliminate possible breeding sites for mosquitoes to avoid a possible outbreak ofdengue fever in the region, while the recent rain has further weakened the surveillance system ...

More dengue cases recorded in Soccsksargen Region

Manila Bulletin - ‎Apr 3, 2013‎

KORONADAL CITY, South Cotabato - The Department of Health (DOH) in Soccsksargen (Region 12) recorded a total of 1,528 dengue cases in the first three months or 156 percent more compared to cases recorded during the same period last year. DoH-12 ...

7 people die of dengue fever in Semarang

GlobalPost - ‎Apr 4, 2013‎

"Of 696 patients with dengue fever during the first three months of this year, seven have died of the mosquito-borne viral infection," Mada G. Soebowo, the head of the Semarang health office`s disease control and prevention section, said here on Thursday.

Salima for steps against dengue

The News InternationaL - ‎Apr 3, 2013‎

Salima Hashmi said that due to change of weather the atmosphere is conducive for dengue mosquito breeding, therefore, the Health Department as well as other concerned departments should pay more attention towards this issue.


JOURNAL ARTICLES

Design, structure-activity relationship and in vivo efficacy of piperazine analogues of fenarimol as inhibitors of Trypanosoma cruzi.

Keenan M, Alexander PW, Diao H, Best WM, Khong A, Kerfoot M, Thompson RC, White KL, Shackleford DM, Ryan E, Gregg AD, Charman SA, von Geldern TW, Scandale I, Chatelain E.

Bioorg Med Chem. 2013 Apr 1;21(7):1756-63. doi: 10.1016/j.bmc.2013.01.050. Epub 2013 Jan 31.

PMID: 23462713 [PubMed - indexed for MEDLINE]

α-Selective glycosylation affords mucin-related GalNAc amino acids and diketopiperazines active onTrypanosoma cruzi.

Martins-Teixeira MB, Campo VL, Biondo M, Sesti-Costa R, Carneiro ZA, Silva JS, Carvalho I.

Bioorg Med Chem. 2013 Apr 1;21(7):1978-87. doi: 10.1016/j.bmc.2013.01.027. Epub 2013 Feb 8.

PMID: 23415086 [PubMed - indexed for MEDLINE]

Praziquantel treatment in trematode and cestode infections: an update.

Chai JY.

Infect Chemother. 2013 Mar;45(1):32-43. doi: 10.3947/ic.2013.45.1.32. Epub 2013 Mar 29. Review.

PMID: 24265948 [PubMed] Free PMC Article

Identification of protein complex associated with LYT1 of Trypanosoma cruzi.

Lugo-Caballero C, Ballesteros-Rodea G, Martínez-Calvillo S, Manning-Cela R.

Biomed Res Int. 2013;2013:493525. doi: 10.1155/2013/493525. Epub 2013 Mar 17.

PMID: 23586042 [PubMed - indexed for MEDLINE] Free PMC Article

TcVac3 induced control of Trypanosoma cruzi infection and chronic myocarditis in mice.

Gupta S, Garg NJ.

PLoS One. 2013;8(3):e59434. doi: 10.1371/journal.pone.0059434. Epub 2013 Mar 26.

PMID: 23555672 [PubMed - indexed for MEDLINE] Free PMC Article

Conventional serological performance in diagnosis of Chagas' disease in southern Brazil.

Araújo AB, Berne ME.

Braz J Infect Dis. 2013 Mar-Apr;17(2):174-8. doi: 10.1016/j.bjid.2012.10.013. Epub 2013 Feb 28.

PMID: 23453943 [PubMed - indexed for MEDLINE]

Trypanosoma cruzi infection in Didelphis virginiana in relation to population parameters and variables associated with presence in rural community dwellings in Yucatan, Mexico.

Parada-López J, Hernández-Betancourt SF, Ruiz-Piña HA, Escobedo-Ortegón FJ, Medina-Peralta S, Panti-May JA.

Ecohealth. 2013 Mar;10(1):31-5. doi: 10.1007/s10393-013-0819-5. Epub 2013 Feb 13. No abstract available.

PMID: 23404037 [PubMed - indexed for MEDLINE]

Discrete typing units of Trypanosoma cruzi identified in rural dogs and cats in the humid Argentinean Chaco.

Enriquez GF, Cardinal MV, Orozco MM, Lanati L, Schijman AG, Gürtler RE.

Parasitology. 2013 Mar;140(3):303-8. doi: 10.1017/S003118201200159X. Epub 2012 Oct 12.

PMID: 23058180 [PubMed - indexed for MEDLINE] Free PMC Article

Epidemiological profile of Trypanosoma cruzi-infected mothers and live birth conditions in the state of Minas Gerais, Brazil.

Pinto FS, de Andrade GM, Januario JN, Maia MC, Gontijo ED.

Rev Soc Bras Med Trop. 2013 Mar-Apr;46(2):196-9.

PMID: 23740060 [PubMed - indexed for MEDLINE] Free Article

Praziquantel treatment in trematode and cestode infections: an update.

Chai JY.

Infect Chemother. 2013 Mar;45(1):32-43. doi: 10.3947/ic.2013.45.1.32. Epub 2013 Mar 29. Review.

PMID: 24265948 [PubMed] Free PMC Article

Neglected tropical diseases: comparison of the costs of integrated and vertical preventive chemotherapy treatment in Niger.

Leslie J, Garba A, Boubacar K, Yayé Y, Sebongou H, Barkire A, Fleming FM, Mounkaila I, Adamou S, Jackou ML.

Int Health. 2013 Mar;5(1):78-84. doi: 10.1093/inthealth/ihs010. Epub 2013 Jan 3.

PMID: 24029850 [PubMed - in process]

Risk factors for intestinal parasitosis, anaemia, and malnutrition among school children in Ethiopia.

Mahmud MA, Spigt M, Mulugeta Bezabih A, López Pavon I, Dinant GJ, Blanco Velasco R.

Pathog Glob Health. 2013 Mar;107(2):58-65. doi: 10.1179/2047773213Y.0000000074.

PMID: 23683331 [PubMed - indexed for MEDLINE]

Biomphalysin, a new β pore-forming toxin involved in Biomphalaria glabrata immune defense against Schistosoma mansoni.

Galinier R, Portela J, Moné Y, Allienne JF, Henri H, Delbecq S, Mitta G, Gourbal B, Duval D.

PLoS Pathog. 2013 Mar;9(3):e1003216. doi: 10.1371/journal.ppat.1003216. Epub 2013 Mar 21.

PMID: 23555242 [PubMed - indexed for MEDLINE] Free PMC Article

Anal polyp caused by Schistosoma mansoni.

Raso P, Sander EM, Raso LA, Andrade Filho Jde S.

Rev Soc Bras Med Trop. 2013 Mar-Apr;46(2):252-4. doi: 10.1590/0037-8682-1681-2013.

PMID: 23740071 [PubMed - indexed for MEDLINE] Free Article

Modulation of innate antigen-presenting cell function by pre-patent schistosome infection.

Ferragine CE, Walls CD, Davies SJ.

PLoS Negl Trop Dis. 2013;7(3):e2136. doi: 10.1371/journal.pntd.0002136. Epub 2013 Mar 21.

PMID: 23556020 [PubMed - indexed for MEDLINE] Free PMC Article

Accuracy of urine circulating cathodic antigen test for the diagnosis of Schistosoma mansoni in preschool-aged children before and after treatment.

Coulibaly JT, N'Gbesso YK, Knopp S, N'Guessan NA, Silué KD, van Dam GJ, N'Goran EK, Utzinger J.

PLoS Negl Trop Dis. 2013;7(3):e2109. doi: 10.1371/journal.pntd.0002109. Epub 2013 Mar 21.

PMID: 23556011 [PubMed - indexed for MEDLINE] Free PMC Article

Repeated Schistosoma japonicum infection following treatment in two cohorts: evidence for host susceptibility to helminthiasis?

Carlton EJ, Hubbard A, Wang S, Spear RC.

PLoS Negl Trop Dis. 2013;7(3):e2098. doi: 10.1371/journal.pntd.0002098. Epub 2013 Mar 7.

PMID: 23505589 [PubMed - indexed for MEDLINE] Free PMC Article

Surveillance on the status of immune cells after Echinnococcus granulosus protoscoleces infection in Balb/c mice.

Pan W, Zhou HJ, Shen YJ, Wang Y, Xu YX, Hu Y, Jiang YY, Yuan ZY, Ugwu CE, Cao JP.

PLoS One. 2013;8(3):e59746. doi: 10.1371/journal.pone.0059746. Epub 2013 Mar 26.

PMID: 23555767 [PubMed - indexed for MEDLINE] Free PMC Article

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"Give a man health and a course to steer, and he'll never stop to trouble about whether he's happy or not."

- George Bernard Shaw