Thursday, April 14, 2016

NTD’s in the news for the week of 27 Mar - 2 Apr 2016

Undark Magazine
And yet, the literature on controlling the mosquitoes that carry the virus is woefully lacking, according to a new meta-analysis published in PLOS Neglected Tropical Diseases. 

EurekAlert (press release)
In addition, GHIT will provide US$1,690,711 to develop treatments for two neglected tropical diseases that torment billions: leishmaniasis, a parasitic disease transmitted by sand flies that, in the cutaneous forms, causes disfiguring skin ulcers, and ...

The Guardian
Product development partnerships, such as the Medicines for Malaria Venture (MMV) and the Drugs for Neglected DiseasesInitiative, use public and philanthropic funds to invest in early-stage research into certain infectious diseases, coordinating the...

Daily Star Gazette
Some of those new drugs could transform treatment of diseases, including certain cancer types, heart disease, hepatitis C, respiratory conditions, rare disorders such as muscular dystrophy, neglected tropical diseases and autoimmune disorders.

NPR
Migrants in Thailand are also more likely to suffer from and seek treatment for communicable diseases like tuberculosis, syphilis, leprosy, malaria and elephantiasis. In the decade leading up to the change in policy, many organizations had already set ...

gurtong
The trained teams, supported by technical experts spent four weeks in the field mapping of Schistosomiasis, Soil Transmitted Helminths and Lymphatic Filariasis in 31 Counties to determine the incidence, prevalence and the geographical distribution of ...

Biotechin.Asia
Apart from using smart mapping technology in the battle against Ebola, the technology was also used to combat diseases such as malaria, dengue, trachoma (the leading cause of preventable blindness), the H1N1 virus (swine flu virus), and many others.

Global Network for Neglected Tropical Diseases’ “End the Neglect”: Tackling Five NTDs in Colombia’s Amazonia Region “…The Global Network for Neglected Tropical Diseases, in partnership with the AbbVie Foundation and Sinergias — Alianzas Estratégicas para la Salud y el Desarrollo Social, with support from the Colombian Ministry of Health and provincial and local health staff,…

POLITICO: The Zika loopholes Willo Brock, senior vice president of external affairs for the Global Alliance for TB Drug Development; Rachel M. Cohen, regional executive director for the Drugs for Neglected Diseases Initiative North America; Jason Cone, executive director of Médecins Sans Frontières (MSF)-USA; and Lindsay McKenna, TB/HIV project officer for the Treatment Action Group…

Medical Xpress
Other parasitic diseases common in many – mostly tropical – parts of the world are Leishmaniasis, River Blindness and Elephantiasis. 

DestinyConnect
Viral infections include trachoma hepatitis A, gastroenteritis and Murray Valley encephalitis. People who live around rubbish are also very vulnerable to parasites like hookwoorms, tapeworms and roundworms, the Australian study found. 

Financial Express Bangladesh
... any form of sanitation facility and therefore practice open defecation, resulting in high levels of environmental contamination and exposure to the risks of microbial infections, diarrhoeal diseases (including cholera), trachoma, schistosomiasis ...

Chagas disease / American trypanosomiasis (Trypanosoma cruzi, T. cruzi) 
North Carolina Health News
Some “proof of concept” studies have shown bedbugs could, under the right circumstances, transmit Bartonella or Chagas disease, a deadly problem concentrated in Central and South America, said DeVries. 

Pasadena Health
Daily Star GazetteThe insect, also called the triatomine bug, resembles a cockroach and has been known to carry a parasite that causes Chagas disease, which can be fatal if left untreated, the CDC said. 

Daily News
The infection benznidazole addresses, Chagas disease, is on the Food and Drug Administration's list of diseases in line for a priority review voucher. Good for a streamlined ride through the FDA, such vouchers have sold for hundreds of millions of dollars.

Drug Target Review 
...atment of Chagas' disease, using genome editing technology and a high throughput activity assay for Trypanosoma cruzi (the cause of the ..

Cysticercosis / Taeniasis (Taenia solium, T. solium)
Daily Star Gazette
Instead, he must have eaten some kind of salad or unwashed food that was contaminated with eggs. The tapeworm eggs made it into his intestine and eventually the larvae made it into his brain, a condition known as Cysticercosis, according to the Centers ...

Pengembangan Metode Diagnosis Penyakit Infeksi (Infectious Disease Diagnosis Method Development)
Republika Online
Penyakit infeksi tropis, seperti demam berdarah dengue (DBD), chikungunya, rabies, lepra, ulkus buruculi, dracunculiasis, penyakit chagas, trachoma, dan cysticercosis. "Diperkirakan lebih dari seperenam penduduk dunia menderita satu atau lebih penyakit ...

Dengue
Buenos Aires Herald
The first two people diagnosed with dengue fever in Argentina died yesterday in Buenos Aires City, according to the BA City Health Ministry, with more than 18,900 cases so far confirmed nationwide.

The Sun Daily
KUALA LUMPUR: About 2,000 residents of Seri Penara Flats in Cheras today were educated on how to eradicate the Aedes mosquito in a campaign titiled 'War On Dengue: Cleaning Up. Saving Life'. 

GMA News
The government will push through with the giving of free and new dengue vaccines to public school students next week even without any recommendation yet from the World Health Organization (WHO). In a media conference on Thursday, Dr. Rose Capeding ...

New Scientist
The mosquito-borne disease dengue usually causes only flu-like symptoms but it can be lethal, especially to children. “My youngest is bitten constantly,” says Steven Barnes, who lives ...

Townsville Bulletin
Eliminate Dengue Townsville had planned to start work in Rowes Bay and Pallarenda in the second half of the year, but two cases have prompted them to bring the program forward to next month. A locally transmitted dengue case was confirmed in ...

Hawaii 24/7 (press release)
The response to the ongoing Dengue Fever outbreak continues. As of 1 p.m. Friday (April 1) the State Department of Health had reported no new confirmed cases of dengue fever since yesterday. Everyone should be reminded that this outbreak remains ..

Big Island Now
No new cases of dengue fever have been reported on the Big Island since March 23. The case count remains at 263 with no cases as risk of infecting mosquitoes, according to the Hawai'i Department of Health. In total, 237 Big Island residents have been ..

Colombo Page
Apr 01, Colombo: Sri Lanka's Ministry of Health says over 340,000 locations were inspected island wide during the first three days of the Dengue Mosquito Control Week declared this week.

Inquirer.net
THE DEPARTMENT of Foreign Affairs has warned the Philippine Sports Commission of the danger posed by the dengue and Zika virus to athletes seeing action in and sports fans heading for the Rio de Janeiro Olympics. 

Nouse
Dengue who? Dengue is another virus wreaking havoc across the tropics but it isn't grabbing headlines in the same way that malaria and Zika do. Yet it might be the key to bringing mosquito-borne diseases under control. Symptoms of dengue infection ..

New Straits Times Online
PUTRAJAYA: A massive two-month operation will be carried out starting from April 11 to combat dengue with checks nationwide. Health Minister Datuk Seri Dr S. Subramaniam said the operation would involve various agencies including the police and armed ...

Hawaii 24/7 (press release)
The response to the ongoing Dengue Fever outbreak continues. As of 1 p.m. Thursday (March 31) the State Department of Health had reported no new confirmed cases of dengue fever since yesterday. Everyone should be reminded that this outbreak remains ...

Times of India
Bhopal: Health department declared a dengue alert in Bhopal district on Thursday. The alert comes close on the heels of 23 dengue positive cases were reported from neighbouring Sehore district. 

Big Island Now
No new cases of dengue fever were confirmed by the Hawai'i Department of Health on Thursday. The overall case count remains at 263, with no cases listed as “potentially infectious” to mosquitoes. In total, 237 Big Island residents have been infected ...

CNN Philippines
Metro Manila (CNN Philippines) — The Health department's anti-dengue vaccination to nine-year-old public school students from Regions 3, 4-A, and the National Capital Region (NCR) will push through next week, even if the World Health Organization ...

Pakistan Today
A total 340 dengue fever cases had been reported in Sindh province since 1st January 2016, out of which 325 were detected from Karachi, five from Hyderabad, two from Sukkur, one each from Tando Muhammad Khan, Jamshoro, Mirpurkhas, Sanghar, ..

gulfnews.com
“The selection of areas and age group for the implementation of the dengue vaccine in the Philippines is backed by evidence. These are selected according to: burden of disease, prevalence, and mortality rate gathered through the Philippine Integrated ...

Wall Street Journal
RIBEIRÃO PRETO, Brazil—While global health agencies struggle to tame the rapidly spreading Zika virus, an older and deadlier pathogen is straining medical providers and setting record infection levels in Brazil:dengue. 

Hawaii 24/7 (press release)
The response to the ongoing DengueFever outbreak continues. As of 1 p.m. Wednesday (March 30) the State Department of Health had reported no new confirmed cases of dengue fever since yesterday. Everyone should be reminded that this outbreak ...

Big Island Now
No new cases of dengue fever have been reported on the Big Island in the past week, holding the overall confirmed case count at 263. None of the cases confirmed are “potentially infectious” to mosquitoes. 

Pakistan Today
Punjab Chief Secretary Khizar Hayat Gondal has directed all divisional commissioners to improve mechanism for dengue surveillance and reporting and take special measures for ensuring availability of anti-mosquito spray.

Hindustan Times
The health department as well as the Ludhiana Municipal Corporation (LMC) would be starting fogging from April 1onwards to check the spread of malaria, dengue, diarrhea and other vector and water borne diseases. 

Manila Bulletin
The Provincial Health Office said that the number of dengue cases for the quarter was lesser compared to the same period in 2015. The PHO nevertheless retained a province-wide dengue alert. Health Education Promotion Officer II Annabelle R. Dilig said ..

Hawaii 24/7 (press release)
The response to the ongoing DengueFever outbreak continues. As of 1 p.m. Tuesday (March 29) the State Department of Health had reported no new confirmed cases of dengue fever since yesterday. 

St, Thomas Source 
The Virgin Islands Department of Health reported no new cases of Zika this week, though it did confirm four case of dengue. The total count for Zika cases remains at 12, with 11 on St. Croix and one on St. Thomas. 

Malay Mail Online
The hot weather has reduced the number of dengue cases as there is no water for mosquitoes to breed in. AFP pic KUALA LUMPUR, March 30 — The hot and arid conditions has contributed to a decline in the number of dengue cases in the country

Outbreak News Today
In 2015, Thailand saw more than 140,000 dengue cases total. In neighboring Malaysia to the south, the numbers are even more dramatic. From the beginning of the year through Mar. 28, 35,586 dengue cases were reported. 

Manila Bulletin
Education Secretary Armin Luistro has directed personnel of the Department of Education (DepEd) – particularly regional directors, schools division superintendents and other school officials – to provide “full support” to the expanded School-Based ..

InterAksyon
MANILA, Philippines -- The Department of Health (DOH) said on Monday it is set to launch its free dengue vaccination program among grade 4 students (nine to 10 years old) in public schools in the National Capital Region (NCR), Central Luzon and ...

Asian Scientist Magazine
AsianScientist (Mar. 29, 2016) - by Law Yao-Hua - A promising vaccine candidate to protect against dengue fever is undergoing a clinical trial in Brazil and could result in a new vaccine next year. The work was published in Science Translational Medicine

The Nation
Rawalpindi - Commissioner Rawalpindi has stressed the need for coordinated efforts to timely check hot spots and effective indoor outdoor surveillance so that anti-dengue measures could be made fruitful. In a meeting here yesterday, the commissioner ...

GMA News
The Department of Health will start giving free dengue vaccinations to public school students on Monday, April 4, a report on Unang Balita on Tuesday said. Health Secretary Janette Garin said the vaccination program will initially be offered to ..

ABC Online
Up to 10 extra public health officers will this week head to the Torres Strait, off far north Queensland, to tackle the region's worst dengue fever outbreak in more than a decade. 

Rappler
MANILA, Philippines – The Department of Health (DOH) on Monday, March 28, dispelled safety concerns on the dengue vaccine that is set to be administered to Filipino schoolchildren starting April. 

Manila Bulletin
SINGAPORE — Sanofi Pasteur, the vaccines division of Sanofi, is pleased to announce the company's denguevaccine, Dengvaxia ®, received the award for “The Vaccine Breakthrough of 2016 at the 6th annual Biopharma Industry Awards Event in ..

Daily Mail
Health department seeks weather reports to help battle swine flu and dengueDaily MailIn order to deal with cases of swine flu and dengue in the national Capital, the health department will be seeking suggestions from the Met Department. Regular meetings will be held with Met officials to enquire about upcoming weather conditions before ..

Ars Technica
The Dengue virus comes in four distinct but related varieties called serotypes, and they're all bad. Rather than inducing tolerance for each other, infection with one Dengue serotype actually makes people more sensitive to the other three. 

Tempo.co
TEMPO.CO, Bekasi - Bekasi City Government reported that the number of dengue fever patients in the city in the period of 2016 (January – March) has reached 1,100 people. At least 17 of them have died. Nevertheless, the city government has not declared ..

Malay Mail Online
Deputy Health Minister Datuk Seri Dr Hilmi Yahaya said for the 12th week, there were 1,877 cases of dengue reported compared to the 11th week with 1,990 cases and two deaths.

The Nation
Rawalpindi - Rawalpindi health department has inducted 55 vaccinators and 76 public health workers (PHWs) to carry out anti-dengue drive in the district. The new hirers will be included in anti-dengue team on April 1 after they submit their joining ..

Pakistan Today
A total 328 dengue fever cases had been reported in Sindh province since January 1, 2016, out of which 313 were detected from Karachi, five from Hyderabad, two from Sukkur, one each from Tando Muhammad Khan, Jamshoro, Mirpurkhas, Sanghar, Ghotki, ..

Human African trypanosomiasis / Sleeping sickness
AFKInsider
Until now, manned aircraft have been delivering male tsetse flies that were raised in labs and sterilized using radiation to infested areas of Ethiopia. Released in the wild, the males mate with fertile females, making them unproductive. 

Nature.com
Labosamide A and B inhibited the growth inhibition of Trypanosoma brucei (IC50 <10 μM), the causative agent of human African trypanosomiasis. Compound 1 exhibited more potent growth inhibitory activity against T. brucei (IC50 0.25 μM) than those of ...

Street Edition
... stages of research and development which include AN3365. The Company's compound AN5568 (SCYX-7158) is licensed to Drugs for Neglected Diseases initiative (DNDi) for the potential treatment of human African trypanosomiasis (sleeping sickness).

Leishmaniasis
Healio
Skin sores due to cutaneous leishmaniasis may heal on their own; however, Leishmania can spread from the skin to the nasooropharyngeal mucosa and cause mucosal leishmaniasis, the release said. 

Leprosy / Hansen's disease (Mycobacterium leprae, M. leprae)
The Nation
World Health Organization (WHO) representative Dr Chris Schmotzer stressed regular and complete medical treatment of leprosy patients as it could cause disability and blindness if left untreated. 

The Japan Times
In early March, lawyers urged former leprosy patients in Japan to file for state compensation over decades of mistreatment before their right to make such claims expire at the end of the month. 

Asahi Shimbun
KUMAMOTO--More than 500 relatives of Hansen's disease patients joined a mass lawsuit on March 29 seeking compensation for the government's decades-long policy of segregating sufferers of the disease from society.

The Japan News
The Hansen's Disease Museum, which opened in 1993 and later became a national museum, is located next to Tama Zenshoen. Many of the exhibited items depict a sad history of segregation. A water pump truck and hose cart stand out. 

Asahi Shimbun
Nearly 40 percent of Hansen's disease sufferers living in national sanatoriums still go by aliases there to keep their families from being ostracized by society, an Asahi Shimbun survey has found. 

Lymphatic filariasis / Elephantiasis
Science Daily
Regular administration of preventive chemotherapy (PC) to at-risk populations is a key step toward elimination of lymphatic filariasis--commonly known as elephantiasis--an NTD still affecting an estimated 40 million people and one of the leading causes ...

SaportaReport
In a country with poor infrastructure, mosquito breeding sites are abundant and can give rise to the various types of mosquitoes that spread lymphatic filariasis, Zika virus, chikungunya and malaria among the nation's 10 million inhabitants. 

Rabies
CBC.ca
Ontario is set to start dropping more anti-rabies vaccine as part of its new phase in its fight against the virus, which has so far been found in 70 raccoons and skunks. Chris Davies, head of wildlife research with the province's Ministry of Natural ...

Elmira Star-Gazette
With the return of spring and warmer weather, health officials are concerned about the appearance of a common springtime scourge — rabies. 

Patch.com
After the raccoon was deceased, its brain tissue was sent for rabies testing, yielding positive results. Wright-Locke Farm Executive Director Archie McIntyre was able to react quickly once he found out the child had been bitten.

Knoxville News Sentinel
Five pets and three wild animals have tested positive for rabies so far in 2016, the Tennessee Department of Health State Public Health Laboratory said this week. The state confirmed rabies in four dogs in Middle Tennessee, as well as a cat in Johnson ...

SciDev.Net[MANILA] 
A tripartite alliance between the World Health Organization (WHO), the UN Food and Agriculture Organization (FAO) and the World Organisation for Animal Health (OIE) is targeting mass dog vaccination in at-risk areas to combat rabies, which ...

Tech Times
While we should all feel blessed to be surrounded by raccoons, dogs and bats that make our fauna diversity more interesting and exciting, these animals can also be a potential source of rabies, a completely preventable disease that can turn 100 percent ...

WBAY
The only person to survive rabies without a vaccine has given birth to fraternal twins. On March 26, Jeanna Giese-Frassetto and her husband Scot welcomed Carly Ann and Connor Primo, according to a news release from the family. Carly Ann weighed 6 ...

Last year, the Veterinary Service of Ghana warned of more rabies related deaths, as they recorded an acute shortage of dog vaccines. There are fears the number of rabies cases could increase this year as the number of stray dogs continue to increase on ..

Foster's Daily Democrat
19 near their home on Dovetail Lane in Dover and rushed to the emergency room at WDH for treatment and a series of rabies vaccinations. The Thompsons and their dogs, Jack, 11, and Henry, 15, are now in good health.  

Schistosomiasis (Schisto, Bilharzia, Snail Fever)
World Health Organization
MANILA, 30 March 2016 - The World Health Organization (WHO) is working with communities across the Western Pacific Region to improve water safety and prevent water-borne diseases such as schistosomiasis. 

Fox News
Blanton studies schistosomiasis (also known as snail fever or bilharzia) but was not involved in the man's case. The eggs of the parasite can enter the bladder and become deposited on its walls. But then, the body's immune response causes that part of ...

Soil transmitted helminthiases (Ascaris lumbricoides, whipworm, Trichuris trichiura, hookworm, Necator americanus, Ancylostoma duodenale)
Daily Star Gazette
Other worms, such as the hookworms Ancylostoma duodenaleand Necator americanus, are tiny vampires. They puncture the lining of the intestine and drink their host's blood. For all their harmful and icky habits, parasites have a lot in common with a ...

Monthly Prescribing Reference (registration)
Emverm (mebendazole; Impax) chewable tablets are available for the treatment of pinworm, whipworm, common roundworm, common hookworm, and American hookworm in single or mixed infections. 

Daily Star Gazette
As we know, The Roman Empire expanded their empire across three continents, they were neaty people when they attemp global domination, at fact they are is famous for its advanced sanitation – public baths and toilets – but human poop from the region ..

Trachoma 
Vanguard
Pfizer is known across Africa to have donated a lot of medications, antibiotics for treatment of blinding trachoma and now we are working closely from the outset with the Association to ensure they have a platform where their voices will be heard and ...

PR Newswire (press release)
Despite Oman's superb infrastructure and high literacy rate (over 90% of the four million population), blindness due to cataract and trachoma remains a public health problem of great concern in several regions of the sultanate. 


Other Neglected Conditions:
Nodding Syndrome
AllAfrica.com
He added that victims complain of fever, dizziness, trembling and becoming crippled, a situation that has forced residents to suspect it to be nodding syndrome. The latest victims, Fred Karuhanga and his children are being taken care of by Scovia Ndiyo ...

Venomous Snakebite
Ventura County Star
Paramedics on Saturday evacuated a snake bite victim from the La Jolla Valley Trail area just north of the Pacific Coast Highway near Mugu Rock. Authorities were notified of the snake bite at 5:54 p.m. and a crew was sent to assess the patient. 

BBC News
A former Gaddafi family bodyguard who became a bartender in the Australian outback has been bitten by a snake while urinating in a bush. Australian man Gary Peters was bodyguard to Saadi Gaddafi, the son of former Libyan dictator Muammar Gaddafi, but ...

The Cairns Post
The RACQ CareFlight helicopter was called in to rescue to man after he was bitten on the right leg in the town of Gregory Downs, north of Mount Isa, after drinking at the local pub with friends. 

NBC 5 Dallas-Fort Worth
Springtime in North Texas is the time when venomous snakes begin to emerge and experts on all sides agree that the cost antivenom treatment can sting nearly as much as the snakebite itself. 


BLOGS:
Red Cross Blogs (blog)
Diarrhoea and infections such as intestinal worms, trachoma and schistosomiasis are common as people have to take water from contaminated sources such as rivers and pans (open ponds). Repeated bouts of diarrhoea can damage the gut to the point ...

Red Cross Blogs (blog)
Good hygiene is also crucial for the prevention of diseases spread by insects, such as malaria, dengue fever, lymphatic filariasis and Japanese encephalitis. All this disproportionally impacts upon women and girls. 

In the Vaupés province of Colombia live small, ethnically diverse and extremely disperse communities without access to basic health care or medicine to treat common diseases. These communities are hard to reach and even harder to treat for neglected tropical diseases (NTDs). 

This spring, we awarded nearly $400,000 in new grants for neglected tropical disease (NTD) control and elimination activities in 2016. This funding is made possible by generous donations to END7, an international advocacy campaign that seeks to raise the awareness and funding necessary to control and eliminate the seven most common NTDs.


JOURNAL ARTICLES:
by Cristina Herrera, Jéssica Kele A. Macêdo, Andrés Feoli, Teresa Escalante, Alexandra Rucavado, José María Gutiérrez, Jay W. 

by Elodie Granjon, Marie-Laure Dichtel-Danjoy, Esber Saba, Ester Sabino, Lea Campos de Oliveira, Maan Zrein

by Ian W. Pray, Dallas J. Swanson, Viterbo Ayvar, Claudio Muro, Luz M. Moyano, Armando E. Gonzalez, Hector H. Garcia, Seth E. O’Neal, 

by Chaman Saini, Anisuddin Siddiqui, Venkatesh Ramesh, Indira Nath

by Hadush Birhanu, Tadesse Gebrehiwot, Bruno Maria Goddeeris, Philippe Büscher, Nick Van Reet

by Grazielle R. Goes, Peter S. Rocha, Aline R. S. Diniz, Pedro H. N. Aguiar, Carlos R. Machado, Leda Q. Vieira

by Edith A. Fernández-Figueroa, Iván Imaz-Rosshandler, Juan E. Castillo-Fernández, Haydee Miranda-Ortíz, Juan C. Fernández-López, Ingeborg Becker, Claudia Rangel-Escareño

by Peter J. Hotez

by Dziedzom K. de Souza, Eric Yirenkyi, Joseph Otchere, Nana-Kwadwo Biritwum, Donne K. Ameme, Samuel Sackey, Collins Ahorlu, Michael D. Wilson 

by Daniel A Leon Rodriguez, F. David Carmona, Luis Eduardo Echeverría, Clara Isabel González, Javier Martin

by Nils Pilotte, Marina Papaiakovou, Jessica R. Grant, Lou Ann Bierwert, Stacey Llewellyn, James S. McCarthy, Steven A. Williams
by Muhammad Hamza, Maryam A. Idris, Musa B. Maiyaki, Mohammed Lamorde, Jean-Philippe Chippaux, David A. Warrell, Andreas Kuznik, Abdulrazaq G. Habib

by Daniela Pagnozzi, Maria Filippa Addis, Grazia Biosa, Anna Maria Roggio, Vittorio Tedde, Mara Mariconti, Francesca Tamarozzi, Valeria Meroni, Gabriella Masu, Giovanna Masala, Enrico Brunetti, Sergio Uzzau

by María J. Corral, Elena Benito-Peña, M. Dolores Jiménez-Antón, Laureano Cuevas, María C. Moreno-Bondi, José M. Alunda 


OTHER
Weekly / April 1, 2016 / Vol. 65 / No. 12

01 Apr 2016

Online informal sources for disease outbreak monitoring and real-time surveillance of emerging public health threats.
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“To keep the body in good health is a duty... otherwise we shall not be able to keep our mind strong and clear."
- Buddha

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