AllAfrica.com
These include river blindness, snail fever, elephantiasis, sleeping sickness, among others. Global efforts to ... The geographic distribution of parasitic infections including malaria and most neglected tropical diseases such as schistosomiasis is very ...
AllAfrica.com
In Mozambique, the most prevalent NTDs include schistosomiasis, trachoma, intestinal parasites, lymphatic filariasis and onchocerciasis. MDA has been implemented for a range of NTDs over recent years, but efforts to engage with affected communities ...
Infection Control Today
In their 2015 declaration “Transforming our world: the 2030 Agenda for Sustainable Development,” World Health Organization (WHO) member states ...
VICE News:
Zika Virus, ‘Ghostbusters,’ and the Strange New Normal of Tropical Disease Pandemics Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine, president and director of the Sabin Vaccine Institute and Texas Children’s Hospital Center for Vaccine Development, Baker Institute fellow in disease and poverty at Rice University,…
Buruli Ulcer / Mycobacterium ulcerans
DESIGUALDAD TATUADA EN LA PIEL (INEQUALITY TATTOOED ON THE SKIN)
radiopolar.com
De esta manera describe Boris, nigeriano de 28 años, las consecuencias de la úlcera de Buruli, la enfermedad misteriosa de la cual se desconoce el origen.
Chagas disease / American trypanosomiasis (Trypanosoma cruzi, T. cruzi)
Investigadores argentinos y un importante hallazgo sobre el Chagas (Argentine researchers and an important finding about Chagas)
Mirada Profesional
Según cifras oficiales del Programa Nacional de Chagas, se calcula que en el país existen 1 millón 600 mil personas infectadas por Trypanosoma cruzi, el parásito causante de la enfermedad, una cifra que representa casi el 4 por ciento de la población ...
3BL Media (press release)
Though the last decade has seen an unprecedented level of coordinated global efforts to fight protozoan parasitic diseases, with some tangible progress made against diseases such as malaria and sleeping sickness for which mortality and morbidity are at ...
VICE News
Texas has consistently led the nation in West Nile virus infections, and it is one of the only states where Chagas disease is transmitted by kissing bugs. Samples collected in Houston from 2003 to 2005 found dengue in the spring and summer.
genomeweb
...y chagasic cardiomyopathy, a condition caused by infection with the Chagas-disease-causing parasite Trypanosoma cruzi and often resulting in heart ..
Nature.com
The infective trypomastigote forms of Trypanosoma cruzi, subvert the inflammatory capacity of macrophages by activating Smad 2 nuclear translocation and inducible NO synthase enzyme degradation in host cells.
Cysticercosis / Taeniasis (Taenia solium, T. solium)
Dove Medical Press
T. solium teniasis-cysticercosis is considered a parasitic “Neglected Tropical Diseases” endemic throughout Southeast Asia. NCC in children has pleomorphic manifestations depending on the location, number and viability of the cysts, and host response
Dengue
The Express Tribune
The continuous rain is also a cause of concern for district managers, as their ongoing anti-dengue campaign has badly been affected. Speaking to The Express Tribune, Water and Sanitation Agency (WASA) spokesperson Umer Farooq said the met office had ..
The Express Tribune
After South, District East — comprising Gulshan and Jamshed towns — also has a high number of dengue cases, shared Dr Solangi, adding that the lowest number of cases are reported from District Malir.
Hawaii 24/7 (press release)
The response to the ongoing Dengue Fever outbreak continues. As of 1 p.m. Friday (March 11) the State Department of Health has reported no new confirmed cases of dengue fever since yesterday.
Chandigarh Tribune
“People should protect themselves both from swine flu and dengue. I have called a meeting tomorrow. We will look after the arrangements for handling dengue cases. The department will soon start a drive to check mosquito breeding at homes,” he said
Press Herald
Failure of mosquito spraying to stop dengue raises questions for battle against Zika. The World Health Organization says 'evidence is missing' that the classical ways of fighting dengue have made any substantial dent in cases – and this might also ...
The Nation
Rawalpindi - Additional Deputy Commissioner General (ADCG), Imran Qureshi Friday said that all resources were being utilized for dealing with Dengue and concerned departments were fully mobilized to cope with the situation.
Big Island Video News
The response to the ongoing DengueFever outbreak continues. As of 1:00 this afternoon the State Department of Health has reported no new confirmed case of dengue fever since yesterday.
The Arunachal Times
Appreciating the health department for conducting such meeting for awareness, East Siang Zilla Parishad Chairman, Kaling Dai has urged the PMC councilors and PRI leaders to organize mass awareness programme on Dengue and other mosquito born ..
The Straits Times
A 63-year-old woman from Bedok North died on Thursday after coming down with dengue.. Read more at straitstimes.com.63-year-old Singaporean woman dies from dengue - Channel ...
Pakistan Today
According to the weekly report issued by Dengue Prevention and Control Programme Sindh, 23 new dengue fever cases were detected in Sindh province, out of which 21 happened in Karachi and one each in Sukkur and Thatta from March 4 to 10, 2016
DAWN.com
RAWALPINDI: The first dengue patient of the year landed in Holy Family Hospital this week but the patient is not local. Nasir Mehar, 24, belongs to Jund in Attock district.
KHON2
“We have been cautiously optimistic about the slowdown of cases over the last few weeks,” said Darryl Oliveira, administrator of the Hawaii County Civil Defense Agency and incident commander of the Hawaii Island dengue response. “Our plan has always ...
Chandigarh Tribune
“People should protect themselves both from swine flu and dengue. I have called a meeting tomorrow. We will look after the arrangements for handling dengue cases.
Outbreak News Today
Since then, 570 suspected cases and 17 confirmed have been reported in the country, with six out of 10 cases reported from the capital city of Montevideo.
World Health Organization
On 1 March 2016, the National IHR Focal Point of Uruguay provided PAHO/WHO with an update on the country's ongoing dengue outbreak..
Business Insider
GENEVA (AP) — The World Health Organization says that traditional insecticide spraying has had no significant impact in slowing dengue, raising major questions about how officials might stop the spread of the Zika virus, also spread by mosquitoes.
Big Island Video News
HAWAII ISLAND – The state health department has released a new dengue fever risk map, and it appears Hawaii Island is on the verge of ending the ...
Silicon Valley's Metro
“IF WE COULD make people smell and taste the show, we would,” says Rafael Pereira, one half of Lima, Peru-based tropical bass duo, Dengue Dengue Dengue!
Deutsche Welle
WHO Assistant Director General Marie-Paule Kieny said experts concurred there was no evidence that traditional mosquito control methods had had any significant impact on transmission of dengue, a virus close to Zika.
NDTV
Dengue killed 60 patients in Delhi alone last year while 99,913 cases were reported all over the country. (Representational Image). No existing drug can treat ...domain-b.com : End-game fordengue as Indian scientists develop ...
Manila Bulletin
Balanga City, Bataan – Cases of dengue fever in Bataan are on the rise and accounted for one of the highest number of recorded cases in Central Luzon so far ...
ABC News
The World Health Organization says that traditional insecticide spraying has had no significant impact in slowing dengue, raising major questions about how officials might stop the spread of the Zika virus, also spread by mosquitoes.
Manila Bulletin
Trece Martires City, Cavite – The number of dengue cases in Cavite province is exhibiting a downward trend, said provincial health officials, who, however, reminded the public not to let their guards down as dengue virus-carrying mosquitoes can strike ..
Townsville Bulletin
EliminateDengue has been successfully transferring Wolbachia bacteria from other insects into Aedes aegypti mosquitoes in Townsville since 2014. The program is proving to stop the spread of dengue and also the Zika virus among insect populations…
West Hawaii Today
KAILUA-KONA — Tuesday marked the 14th consecutive day state health officials have confirmed no new cases of dengue fever on Hawaii Island. No new cases of the mosquito-borne virus have been confirmed since Feb. 24.
International Federation of Red Cross and Red Crescent Societies
More than 200,000dengue cases were reported in the Philippines last year – an increase of 80,000 cases compared with 2014.
Imperial Valley Press
Public health officials launched Monday the First National Campaign Against Zika, Dengue and Chikungunya, in order to prevent residents from getting ill. Health Services Director Rigoberto Isarraraz led a health fair with education training and ..
The Star Online
MANY people have given the thumbs-up for the state government's move to have weekly talks during the morning assembly sessions in schools as part of efforts to combat the dengue menace.
The Star Online
SCHOOL CHILDREN should be agents of change in combating dengue, says Perak Health Committee Chairman Datuk Dr Mah Hang Soon. Dr Mah said this during the launching of an anti-dengue campaign organised by the State Education Department at ..
Daily News & Analysis
A new drug has been launched for the treatment of dengue patients with low platelet counts by the Karnataka Antibiotics and Pharmaceuticals Limited (KAPL), a government enterprise.
St, Thomas Source
The Department of Health confirmed one more case of Zika and no new cases of dengue in the last week. A total of seven cases of Zika have been confirmed since the first case was announced in late January.
Hawaii 24/7 (press release)
The response to the ongoing Dengue Fever outbreak continues. Although the number and frequency of new confirmed cases appears to be on the decline, the outbreak is not anticipated to be considered over anytime in the near future.
Saint Croix Source
The Department of Health confirmed one more case of Zika and no new cases of dengue in the last week. A total of seven cases of Zika have been confirmed since the first case was announced in late January.
Gov.sg (press release)
The number of new dengue cases fell for the second consecutive week, although it remains high for this time of the year, compared to previous years.
West Hawaii Today
Recent tourism data suggests Hawaii Island's dengue fever outbreak hasn't had the overall negative impacts some feared. The month of January saw a year-over-year increase of visitor arrivals of 3.8 percent for the Big Island, with tourist spending ..
Outbreak News Today
According to the studies conducted at Medical Research Institute, there had being continued dengue transmission in 1970s and 1980s with periodic epidemics, without significant numbers of dengue hemorrhagic fever and dengue shock syndrome.
Health Aim
The team of experts behind the herbal dengue drug is planning to hold clinical trials and toxicity studies. Following the trials, the team will approach the Ministry of Ayush and the Drug Controller of India (DCI) for permission on commercial ..
India.com
New Delhi, Mar 8 (PTI): Delhi reported maximum cases of dengue and most deaths caused by it across the country in 2015, Health Minister J P Nadda told the Rajya Sabha today. The year saw almost 150 per cent rise in the number of dengue cases ...
EurekAlert (press release)
Umeå University-led research on mosquito control and Dengue prevention was presented recently at an international conference held in Colombo, Sri Lanka on 24-26 February.
Indiatimes.com
In a breakthrough move that can help in the fight against dengue, a herbal medicine against it is claimed to have been developed by scientists in India, which accounts for 50 per cent of the global population estimated to be at risk from the disease.
Business Standard
A medicine has been launched for the treatment of dengue patients with low platelet counts by the Karnataka Antibiotics and Pharmaceuticals Limited (KAPL), a government enterprise.
Hawaii 24/7 (press release)
The response to the ongoing Dengue Fever outbreak continues. Although the number and frequency of new confirmed cases appears to be on the decline, the outbreak is not anticipated to be considered over anytime in the near future.
Bangkok Post
A public lecture entitled "Dengue Vaccine: A Hope for Thai people" was recently given at Mahidol University's Faculty of Tropical Medicine.
The Star Online
DENGUE fever is a major cause of mortality and morbidity (state of being unhealthy) in our country. Last year, there were 125,000 cases ofdengue, with 325 deaths, reported. One must understand that for these cases, blood tests were done to confirm ...
Folha de S.Paulo
It has been nine months since bank manager Dannylle Campelo, 32, started to have problems to hold her one-year old daughter or give her first-born child, aged four, a bath.
Channel News Asia
SINGAPORE: The number of new cases of dengue reported continued its downward trajectory, with 415 cases reported from Feb 28 to Mar 5, according to the National Environment Agency's latest data on Tuesday (Mar 8).
Big Island Now
Another work week begins with no cases new cases of dengue fever confirmed. The count has remained at 260 confirmed since Feb. 24. The Hawai'i Department of Health has also listed the number of dengue cases “potentially infectious” to mosquitoes at ...
West Hawaii Today
Recent tourism data suggests Hawaii Island's dengue fever outbreak hasn't had the overall negative impacts some feared. The month of January saw a year-over-year increase of visitor arrivals of 3.8 percent for the Big Island, with tourist spending ...
NDTV
New Delhi: In a breakthrough move that can help in the fight against dengue, a herbal medicine against it is claimed to have been developed by scientists in India, which accounts for 50 per cent of the global population estimated to be at risk from the ...
New Straits Times Online
Asked if dengue strains had mutated into a new, more contagious strain, IDRC virology unit research officer Dr Ravindran Thayan said based on sequencing of selected genetic regions of local dengue virus strains, there was no evidence of new dengue ...
Firstpost
New Delhi: In a breakthrough move that can help in the fight against dengue, a herbal medicine against it is claimed to have been developed by scientists in India, which accounts for 50 per cent of the global population estimated to be at risk from the ...
ThaiVisa News
BANGKOK: — Dengue fever remains a concern in Thailand as cases recorded during the past two months of this year has doubled cases in the same period last year.
Viet Nam News
Minister of Health Nguyen Thi Kim Tien (left) inspects Zika virus and dengue fever prevention measures in Tan Truc Town of HCM City's Binh Chanh District on Saturday.
AllAfrica.com
THE recent invention of dengue fever vaccine has been welcomed in the country with hopes that it will go a long way towards efforts to contain the disease which killed four people in Tanzania last year.
West Hawaii Today
KAILUA-KONA — Another day passed Friday with no new confirmed cases of dengue fever on the Big Island, according to the state Department of Health. State health officials said Friday that no new cases have been confirmed on the island since Feb.
Townsville Bulletin
It is the second reported case in the Towers for the week, with the Townsville Public Health Unit initially confirming an imported case of dengue fever from Indonesia on Wednesday.
Malay Mail Online
Gabriela Alves bathes her four-month-old daughter Ana Sophia, who was born with microcephaly, at their house in Olinda, Brazil. The Health Ministry says microcephaly cases in Malaysia are not linked to the Zika virus.
The Straits Times
With bottles of mosquito repellent in hand, 120 grassroots volunteers went door to door in Jurong East yesterday. Jurong East is home to three active dengue clusters, the largest in Jurong East Street 13 with 34 cases.
Malaysiakini (subscription)
Dengue fever is on the rise again, with at least 100 cases being recorded every week. Deputy Health Minister Dr Hilmi Yahaya said the ministry was still actively carrying out anti-Aedes activities to reduce the number of dengue cases.
Big Island Now
No cases of dengue fever have been confirmed on the Big Island for a total of eight straight days. The Hawai'i Department of Health has also not listed any cases as “potentially infectious” to mosquitoes since Feb. 23.
Malay Mail Online
The public are urged to keep their surroundings clean and not just wait for the local authority workers to do the job.
Eurweb.com
I seem to have gotten off of Oahu and back home to California safely, i.e. fever free. Dodged THAT bullet. But damn. Hawaii's governor has for now said he won't declare a statewide emergency until the outbreak spreads to other islands or includes other ...
Star2.com
In 2011, there were 19,884 dengue cases with 36 deaths. In 2015 the number rose to over 120,000 cases with 322 fatalities. This rise is part of a worldwide phenomenon, with cases increasing 30-fold in the past half century.
Dracunculiasis / Guinea worm
News Ghana
Yokouide said all collected data would be entered into a report for international experts to determine the end of the disease in DR Congo. Dracunculiasis, also known as Guinea-worm disease, is an infection caused by the parasite Dracunculus medinensis, ...
Human African trypanosomiasis / Sleeping sickness
Independent Online
Town after town was dying, not only from Khartoum's military onslaught, but from Trypanosomiasis or sleeping sickness spread by the Tsetse fly, which had caused many of the local people to lose their minds.
Leishmaniasis
BU Today
Two CMD compounds were active against the leishmania parasite in cells. More good news arrived eight months later. McKerrow's team had tested the compounds in mice infected with leishmaniasis and found that they significantly reduced the number of ...
Leprosy / Hansen's disease (Mycobacterium leprae, M. leprae)
New Kerala
Kolkata, March 11 : As many as 320 voters of a leprosy colony in West Bengal's Bankura district will have access to upgraded facilities like battery-operated cars ...
Pulitzer Center on Crisis Reporting
Most of the forty-odd men and women have been living at the Hendala Leprosy Hospital have been there for most of their adult lives. There's no medical reason for them to stay. Leprosy is curable and the patients are no longer infectious.
Huffington Post UK
On International Women's Day I want to highlight the plight of many women worldwide living with a neglected tropical disease.
CBS Local
7 at his home in a foothill community north of Los Angeles. Rea helped identify the role of the immune system in the development of leprosy symptoms such as disfiguring skin lesions that had made sufferers of Hansen's disease outcasts since Biblical times
Lymphatic filariasis / Elephantiasis
Republica
Elephantiasis, which is the second major infectious disease after leprosy, causes permanent disability. Over 30,000 people infected with elephantiasis across the country are estimated to have been living with permanent disabilities.
Onchocerciasis / River blindness
The Rider News
...Against River blindness (UFAR) Executive Director Dr. Daniel Shungu. Also known as river blindness, onchocerciasis is a parasitic disease transmitted by ..
Rabies
Coconuts Bali
Rabies is the chief suspect as the cause of death of a little boy in Klungkung, Bali. Nine-year-old AA Gede Arimbawa from Banjarangkan breathed his last breath on March 7, around 5 am at Klungkung Public Hospital, according to Tribun Bali.
Schistosomiasis (Schisto, Bilharzia, Snail Fever)
Truth-Out
For some unknown reason, the species of snails that can better adapt to warm open areas that occur after a forest is cut down are better hosts for parasites called flatworms, some of which cause schistosomiasis, a disease which damages human organs.
Huffington Post
The Conversation Africa The Conversation Africa is a news and analysis website which is a collaboration between academics and journalists.
AllAfrica.com
In Yaounde, statistics indicate that bilharzia has dropped from 40 per cent to 0 per cent at the Nkolbission Primary School, 25 per cent to 2 per cent at the Obogogo primary school as well as the Mballa II primary school from 20 to 0 per cent. ...
Imperial College London
The supplement is a collaboration of many organisations including, RTI International, the Schistosomiasis Control Initiative (SCI), SightSavers, Mectizan Donation Programme, Children Without Worms, National Podoconosis Action Network and WaterAid, ...
VICE News
Schistosomiasis, a devastating parasitic disease that causes damage to the bladder and ulcers in the female genital tract, is the ultimate neglected tropical disease, in no small part because it's often been viewed as affecting only the world's poorest ...
Huffington Post
That same amount could help Schistosomiasis Control Initiative dispense deworming treatments to protect 125 school children against debilitating parasitic infections.
Soil transmitted helminthiases (Ascaris lumbricoides, whipworm, Trichuris trichiura, hookworm, Necator americanus, Ancylostoma duodenale)
Dove Medical Press
Abstract: Ascaris lumbricoides is a neglected parasite that induces changes in host immune response. This study is conducted to define the serum levels of tumor necrosis factor alpha (TNF-α), interleukin-4 (IL-4), and interleukin-5 (IL-5) in some ..
Lei reforça a prevenção às verminoses em escolas municipais e estaduais do Amazonas (Law reinforces the prevention of worms in municipal and state schools in the Amazon)
Portal A Crítica
...ções provocadas por parasitas como a Ascaris lumbricoides (lombriga), o Ancilostomideo (amarelão) e Trichuris trichiura (verme chicote), que se instalam no interior do corpo de ...
Other Neglected Conditions:
Venomous Snakebite
Orlando Sentinel
A man was flown to a hospital after a 911 caller reported he was bitten by a snake near Christmas, an Orange County Fire Rescue spokesman said.
STAT
Snakes, says Dr. Matt Lewin, are “like little mobile landmines”: They're invisible, lying in wait in populated areas, killing or maiming without warning. Worldwide, tens of thousands of people die from snakebites every year. But an existing drug could...
The Hindu
A farmer Mora Bhaskar, 45, died due to snake bite in his agricultural field in Thokalapalle village in Porumamilla mandal in Kadapa district on Thursday. Bhaskar went to switch on the agricultural pumpset in the wee hours when a snake bit him ...
The Hans India
Banswada (Nizamabad): A Class I student of Someshwar Government High School died due to the snake bite on the school premises here at Someshwar village of Banswada mandal on Thursday. He suffered snake bite while playing cricket on the school ...
Cantech Letter
snake A new study provides detailed projections on how snake populations in the Americas will be on the move over the next three decades, thanks to global warming, and forecasts the growing risks of snakebite in various regions of North, Central and ...
The Hindu
Snakebite has remained one of the most neglected of all tropical diseasesdespite the fact that it affects the most impoverished section of the society. Green Cross India has been helping the rural public, particularly agricultural workers, to cope ...
Independent Online
Snake catcher Jason Arnold said he had removed seven snakes from suburban homes around ... The bite was mild, so he didn't require anti-venom.
BLOGS:
Mother Nature Network (blog)
It's no secret that armadillos are capable of contracting and passing along leprosy (as well as Chagas disease). Their low body temperature makes them perfect hosts for Mycobacterium leprae, so it is generally ill-advised to handle them or eat their meat.
Medgadget.com (blog)
Report includes top line data relating onDengue Fever Global clinical trials scenario. This report on DengueFever also includes an review of trial numbers as well as their (DengueFever) average enrollment in uppermost/top countries which are ...
On March 1, student leaders gathered in Washington, D.C., for the second annual END7 Student Advocacy Day. The event brought together 40 students active in END7 programs, from 15 colleges and universities across the country for 39 meetings with Members of Congress and their staff.
BMC Blogs Network (blog)
Parasite phylogeographic and population genetic study shows the human whipworm most likely originated from primates in Africa, designating it a heirloom parasite of humans.
JOURNAL ARTICLES:
by The PLOS Neglected Tropical Diseases Staff
by Britta Stadelmann, Reto Rufener, Denise Aeschbacher, Markus Spiliotis, Bruno Gottstein, Andrew Hemphill The metacestode (larval) stage of the tapeworm Echinococcus multilocularis causes alveolar echinococcosis (AE), a very severe and in many cases incurable disease.
by Henok Negussie, Thomas Addissie, Adamu Addissie, Gail Davey Background Community-based randomized controlled trials are often complex pieces of research with significant challenges around the approach to the community, information provision, and decision-making, all of which are fundamental to the informed consent process.
by Siwi P. M. Wijayanti, Sunaryo Sunaryo, Suprihatin Suprihatin, Melanie McFarlane, Stephanie M. Rainey, Isabelle Dietrich, Esther Schnettler, Roman Biek, Alain Kohl Background No vaccine is currently available for dengue virus (DENV), therefore control programmes usually focus on managing mosquito vector populations.
by Joseph Kamgno, Patrick Nguipdop-Djomo, Raceline Gounoue, Mathurin Téjiokem, Annette C. Kuesel Background Loiasis is a parasitic infection endemic in the African rain forest caused by the filarial nematode Loa loa. Loiasis can be co-endemic with onchocerciasis and/or lymphatic filariasis.
by Valerie A. Paz-Soldan, Karin Bauer, Amy C. Morrison, Jhonny J. Cordova Lopez, Kiyohiko Izumi, Thomas W. Scott, John P. Elder, Neal Alexander, Eric S. Halsey, Philip J. McCall, Audrey Lenhart Dengue is an arthropod-borne virus of great public health importance, and control of its mosquito vectors is currently the only available method for prevention.
by Emebet Adem, Fitsumbirhan Tajebe, Mulusew Getahun, Amare Kiflie, Ermias Diro, Asrat Hailu, Ziv Shkedy, Bewketu Mengesha, Tadele Mulaw, Saba Atnafu, Tekalign Deressa, Biniam Mathewos, Ebba Abate, Manuel Modolell, Markus Munder, Ingrid Müller, Yegnasew Takele, Pascale Kropf One of the key immunological characteristics of active visceral leishmaniasis (VL) is a profound immunosuppression…
by Marcio L. Rodrigues
by Paulo R. Cortes, Laura S. Chiapello, David Dib, Monica V. Herrero, Carmen T. Nuncira, Carlos De Petris, Jose Echenique
by Jack E. T. Grimes, Gemechu Tadesse, Kalkidan Mekete, Yonas Wuletaw, Abeba Gebretsadik, Michael D. French, Wendy E. Harrison, Lesley J. Drake, Iain A. Gardiner, Elodie Yard, Michael R. Templeton Background It is thought that improving water, sanitation, and hygiene (WASH) might reduce the transmission of schistosomes and soil-transmitted helminths, owing to their life cycles.
by Jennifer A. Gilbert, Jan Medlock, Jeffrey P. Townsend, Serap Aksoy, Martial Ndeffo Mbah, Alison P. Galvani Human African trypanosomiasis (HAT), transmitted by tsetse flies, has historically infected hundreds of thousands of individuals annually in sub-Saharan Africa.
by Zachary T. Swinney, Brad A. Haubrich, Shuangluo Xia, Chakk Ramesha, Stephen R. Gomez, Paul Guyett, Kojo Mensa-Wilmot, David C. Swinney Background New therapeutics are needed for neglected tropical diseases including Human African trypanosomiasis (HAT), a progressive and fatal disease caused by the protozoan parasites Trypanosoma brucei gambiense and T. b. rhodesiense.
by Ayako Morimoto, Satoko Omachi, Yasutaka Osada, James K. Chambers, Kazuyuki Uchida, Chizu Sanjoba, Yoshitsugu Matsumoto, Yasuyuki Goto Hemophagocytosis is a phenomenon in which macrophages phagocytose blood cells. There are reports on up-regulated hemophagocytosis in patients with infectious diseases including typhoid fever, tuberculosis, influenza and visceral leishmaniasis (VL).
by Christian Rassi, Dan Kajungu, Sandrine Martin, Jorge Arroz, Jamie Tallant, Celine Zegers de Beyl, Helen Counihan, James N. Newell, Anna Phillips, Jane Whitton, Artur Manuel Muloliwa, Kirstie Graham Background Schistosomiasis is a parasitic disease which affects almost 300 million people worldwide each year. It is highly endemic in Mozambique.
by Philipp Gierok, Christian Kohler, Ivo Steinmetz, Michael Lalk Background Burkholderia pseudomallei is a water and soil bacterium and the causative agent of melioidosis. A characteristic feature of this bacterium is the formation of different colony morphologies which can be isolated from environmental samples as well as from clinical samples, but can also be induced in vitro.
by Saskia Decuypere, Jessica Maltha, Stijn Deborggraeve, Nicholas J. W. Rattray, Guiraud Issa, Kaboré Bérenger, Palpouguini Lompo, Marc C. Tahita, Thusitha Ruspasinghe, Malcolm McConville, Royston Goodacre, Halidou Tinto, Jan Jacobs, Jonathan R. Carapetis
by Bruno de Paulo Ribeiro, Gustavo Capatti Cassiano, Rodrigo Medeiros de Souza, Dalila Nunes Cysne, Marcos Augusto Grigolin Grisotto, Ana Paula Silva de Azevedo dos Santos, Cláudio Romero Farias Marinho, Ricardo Luiz Dantas Machado, Flávia Raquel Fernandes Nascimento Mechanisms involved in severe P. vivax malaria remain unclear.
Currently, schistosomiasis in China provides an excellent example of many of the challenges of moving from low transmission to the elimination of transmission for infectious diseases generally. In response to the surveillance dimension of these challenges, we here explore two strategic approaches to inform priorities for the development of improved methods addressed specifically to schistosomiasis
Background Since the major outbreak in 2007 in the Yap Island, Zika virus (ZIKV) causing dengue-like syndromes has affected multiple islands of the South Pacific region. In May 2015, the virus was detected in Brazil and then spread through South and Central America.
Background Leprosy remains a public health problem in Brazil. Although the overall number of new cases is declining, there are still areas with a high disease burden, such as Pará State in the north of the country.
Background Dengue virus (DENV) is the most prominent arbovirus worldwide, causing major epidemics in South-East Asia, South America and Africa. In 2010, a major DENV-2 outbreak occurred in Gabon with cases of patients co-infected with chikungunya virus (CHIKV).
Leishmania aethiopica is the etiological agent of cutaneous leishmaniasis (CL) in Ethiopia and can cause severe and complicated cases such as diffuse CL (DCL), mucocutaneous leishmaniasis or extensive CL, requiring systemic treatment. Despite the substantial burden, evidence-based treatment guidelines are lacking.
Background There are health risks associated with wastewater and fecal sludge management and use, but little is known about the magnitude, particularly in rapidly growing urban settings of low- and middle-income countries.
Seasonal-long larvicide treatments and/or outdoor space-spray applications of insecticides are frequently applied to reduce Aedes albopictus nuisance in urban areas of temperate regions, where the species has become a permanent pest affecting people’s quality of life and health.
Background The aim of this study is to describe the major evolutionary historical events among Leishmania, sandflies, and the associated animal reservoirs in detail, in accordance with the geographical evolution of the Earth, which has not been previously discussed on a large scale.
Background Although incidence of leprosy in Spain has declined steadily over the years, the fivefold increase in immigration since the turn of the century—much of it from countries where leprosy is still prevalent—has been linked to an uptick in registered cases.
Reactive oxygen and nitrogen species (ROS and RNS) produced by the phagocytic cells are the most common arsenals used to kill the intracellular pathogens. However, Leishmania, an intracellular pathogen, has evolved mechanisms to survive by counterbalancing the toxic oxygen metabolites produced during infection.
Today, the World Health Organization recognizes 17 major parasitic and related infections as the neglected tropical diseases (NTDs). Despite recent gains in the understanding of the nature and prevalence of NTDs, as well as successes in recent scaled-up preventive chemotherapy strategies and other health interventions, the NTDs continue to rank among the world’s greatest global health problems.
Background Protozoan parasites of the genus Leishmania cause a large spectrum of clinical manifestations known as Leishmaniases. These diseases are increasingly important public health problems in many countries both within and outside endemic regions.
Introduction Dengue has emerged as a significant public health problem in Sri Lanka. Historically surveillance was passive, with mandatory dengue notifications based on clinical diagnosis with only limited laboratory confirmation. To obtain more accurate data on the disease burden of dengue, we set up a laboratory-based enhanced sentinel surveillance system in Colombo District.
Background The occurrence of outbreaks of human rabies transmitted by Desmodus rotundus in Brazil in 2004 and 2005 reinforced the need for further research into this zoonosis. Studies of knowledge and practices related to the disease will help to define strategies for the avoidance of new cases, through the identification of gaps that may affect the preventive practices.
by Taylor G. Donaldson, Adalberto A Pèrez de León, Andrew Y. Li, Ivan Castro-Arellano, Edward Wozniak, William K. Boyle, Reid Hargrove, Hannah K. Wilder, Hee J. Kim, Pete D. Teel, Job E. Lopez
by Jack E. T. Grimes, Gemechu Tadesse, Kalkidan Mekete, Yonas Wuletaw, Abeba Gebretsadik, Michael D. French, Wendy E. Harrison, Lesley J. Drake, Iain A. Gardiner, Elodie Yard, Michael R. Templeton Background It is thought that improving water, sanitation, and hygiene (WASH) might reduce the transmission of schistosomes and soil-transmitted helminths, owing to their life cycles.
by Jennifer A. Gilbert, Jan Medlock, Jeffrey P. Townsend, Serap Aksoy, Martial Ndeffo Mbah, Alison P. Galvani Human African trypanosomiasis (HAT), transmitted by tsetse flies, has historically infected hundreds of thousands of individuals annually in sub-Saharan Africa.
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Weekly / March 11, 2016 /65(9)
11 Mar 2016
Online informal sources for disease outbreak monitoring and real-time surveillance of emerging public health threats.
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“Live as if you were to die tomorrow. Learn as if you were to live forever.”
- Mahatma Gandhi
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